Doulah, A., Sadeghian, H. (2011). Novel synthesis of Pyrimido[4,5- e] [1,3,4] thiadiazines. International Journal of Heterocyclic Chemistry, 1(1), 16-20.
Abdolhassan Doulah; Hamid Sadeghian. "Novel synthesis of Pyrimido[4,5- e] [1,3,4] thiadiazines". International Journal of Heterocyclic Chemistry, 1, 1, 2011, 16-20.
Doulah, A., Sadeghian, H. (2011). 'Novel synthesis of Pyrimido[4,5- e] [1,3,4] thiadiazines', International Journal of Heterocyclic Chemistry, 1(1), pp. 16-20.
Doulah, A., Sadeghian, H. Novel synthesis of Pyrimido[4,5- e] [1,3,4] thiadiazines. International Journal of Heterocyclic Chemistry, 2011; 1(1): 16-20.
Novel synthesis of Pyrimido[4,5- e] [1,3,4] thiadiazines
1Department of Nursing, Faculty of Nursing and Midwifery, Islamic Azad University, Ahvaz Branch, Ahvaz
2Department of Laboratory Sciences, School of Paramedical Sciences, Mashhad University of Medical Sciences, Mashhad, Iran
Abstract
Treatment of 1-(5-bromo-2-chloro-6-methylpyrimidin-4-yl)-1-methylhydrazine with dimethylthiocarbamoylchloride gave 7-chloro-N,N,1,5-tetramethyl-1H-pyrimido[4,5-e][1,3,4]thiadiazin-3-amine in basic acetonitrile. The latter compounds were reacted with secondary amines in boiling ethanol to afford the related 7-amino derivatives.
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