Document Type: Original Paper
Department of Chemistry, College of Science, ShahidChamran University, Ahvaz, Iran
1Department of Chemistry, College of Science, ShahidChamran University, Ahvaz, Iran
2Department of Medicinal Chemistry, Faculty of Pharmacy and Pharmaceutical Sciences Research Center, Tehran University of Medical Sciences, Tehran
A novel magnetically immobilized polyethyleneimine (PEI) fabricated by covalently anchoring on MCM-41 (MCM-41@PEI) was prepared. The synthesized catalyst was characterized by Fourier transform infrared (FT-IR), thermogravimetric analysis (TGA), X-ray powder diffraction (XRD), scanning electron microscopy (SEM) and transmission electron microscopy (TEM). The immobilized PEI was shown to be an efficient heterogeneous catalyst for the synthesis of spiro-oxindole and benzopyranes derivatives via multi-component reaction (MCR), in ethylene glycol as a green solvent. No leaching problem was observed after several runs, while the catalyst can be recovered and reused without loss of reactivity under the described reaction conditions.