Synthesis of imidazo[2,1-b]thiazole-3-carboxylate through the reaction of thiohydantoins and ethylbromopyruvate

Document Type: Original Paper

Authors

Young Researchers and Elite Club, Marvdasht Branch, Islamic Azad University, Marvdasht, Iran

Abstract

Imidazo[2,1-b]thiazoles are obtaind in excellent yields from the addition reaction between thiohydantoin and ethylbromopyruvate.  These imidazo[2,1-b]thiazoles in the presence of p-TSA in boiling toluene refluxed for 2.5 hours led to imidazo[2,1-b]thiazole-3-carboxylates in elimination reactions

Keywords