Zarei, N., Mehdi Ghanbari, M., Jamali, M., Kiamarsi, M., Mohagheghzadeh, P. (2011). Synthesis of imidazo[2,1-b]thiazole-3-carboxylate through the reaction of thiohydantoins and ethylbromopyruvate. International Journal of Heterocyclic Chemistry, 1(4), 11-14.
Nasimeh Zarei; Mohammad Mehdi Ghanbari; Marzieh Jamali; Mahboobeh Kiamarsi; Pegah Mohagheghzadeh. "Synthesis of imidazo[2,1-b]thiazole-3-carboxylate through the reaction of thiohydantoins and ethylbromopyruvate". International Journal of Heterocyclic Chemistry, 1, 4, 2011, 11-14.
Zarei, N., Mehdi Ghanbari, M., Jamali, M., Kiamarsi, M., Mohagheghzadeh, P. (2011). 'Synthesis of imidazo[2,1-b]thiazole-3-carboxylate through the reaction of thiohydantoins and ethylbromopyruvate', International Journal of Heterocyclic Chemistry, 1(4), pp. 11-14.
Zarei, N., Mehdi Ghanbari, M., Jamali, M., Kiamarsi, M., Mohagheghzadeh, P. Synthesis of imidazo[2,1-b]thiazole-3-carboxylate through the reaction of thiohydantoins and ethylbromopyruvate. International Journal of Heterocyclic Chemistry, 2011; 1(4): 11-14.
Synthesis of imidazo[2,1-b]thiazole-3-carboxylate through the reaction of thiohydantoins and ethylbromopyruvate
Young Researchers and Elite Club, Marvdasht Branch, Islamic Azad University, Marvdasht, Iran
Abstract
Imidazo[2,1-b]thiazoles are obtaind in excellent yields from the addition reaction between thiohydantoin and ethylbromopyruvate. These imidazo[2,1-b]thiazoles in the presence of p-TSA in boiling toluene refluxed for 2.5 hours led to imidazo[2,1-b]thiazole-3-carboxylates in elimination reactions
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