The inhibition effects of melon on mushroom tyrosinase activity

Document Type: Original Paper

Authors

1 Biology Department, School of Sience, Chamran University

2 Medicina Chemistry Department, School of Pharmacy, Ahwaz Jundishapur University

3 Pharmacognos Department, School of Pharmacy, Ahwaz Jundishapur University.

Abstract

The  inhibition effects seed and peel of melon on diphenolase activity of mashroom tyrosinase were investigated. The IC50 values and Ki values of seed and peel of melon were evaluated. increased the Km value and decreased the Vm value so it show mixed type inhibition on mushroom tyrosinase when L-DOPA was used as a substrate.