SYNTHESIS OF 1,8-DIOXO-OCTAHYDROXANTHENES WITH THIAMINE CHLORIDE IN ECO-FRINDLY AND SOLVENT FREE CONDITION

Document Type: Original Paper

Authors

Department of chemistry, Science and Research Branch, Islamic Azad University, Tehran, Iran

Abstract

A novel, simple and environmentally friendly method is reported for the preparation of 1,8-dioxo-octahydroxanthene derivatives by the reaction of dimedon with various aromatic aldehydes, using thiamine chloride  as a recyclable catalyst under solvent-free conditions. This procedure has following benefits; simple workup, moderate reaction times, good yields, and completely compatible with environment.

Keywords