Razzaghi – asl, N., Mohammadi, M. (2014). Synthesis of thiadiazine-3,7-diamine derivatives. International Journal of Heterocyclic Chemistry, 4(1), 45-54.
Nima Razzaghi – asl; Mohammad Kazem Mohammadi. "Synthesis of thiadiazine-3,7-diamine derivatives". International Journal of Heterocyclic Chemistry, 4, 1, 2014, 45-54.
Razzaghi – asl, N., Mohammadi, M. (2014). 'Synthesis of thiadiazine-3,7-diamine derivatives', International Journal of Heterocyclic Chemistry, 4(1), pp. 45-54.
Razzaghi – asl, N., Mohammadi, M. Synthesis of thiadiazine-3,7-diamine derivatives. International Journal of Heterocyclic Chemistry, 2014; 4(1): 45-54.
1Department of pharmaceutical chemistry , ardabil university of medical sciences , ardabil , iran
2Factually of Science, Ahvaz Branch, Islamic Azad University, Ahvaz, Iran.
Abstract
New 1,5-tetra alkyl methyl- phenyl-1H-pyrimido[4,5-e][1,3,4]thiadiazine-3,7-diamine were synthesized via the cyclocondensation of 2-(5-bromo-2-chloro-6-methylpyrimidin-4-yl)-2-methylhydrazine with phenylthioisothiocyanate and further replacement of chlorine atom on the seven number position of pyrimido[4, 5- e][1, 3, 4]thiadiazin by appropriate secondary amines in simple and efficient methods.
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