New and Efficient Rout for One Pot Synthesis of acenaphtho[1,2-b] quinoxalines

Document Type : Original Paper


Department of Medicinal Chemistry , Mazandaran University of Medical Sciences , Sary, Iran


Acenaphtho derivatives have been reported as antitumor agents. So, the reaction of acenaphthylene-1,2-dione with 3,4-diaminobenzenethiol, and then with the alkyl chloride derivatives for the synthesis of acenaphtho [1,2-b] quinoxalines are reviewed. Excellent yields of the products, short reaction times and simple work-up are attractive features of this suitable protocol.


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