reaction of thiohydantoins and ethylbromopyruvate for Synthesis of imidazo[2,1-b]thiazole 3-carboxylate

Document Type: Original Paper

Authors

1 Young Researchers and Elite Club, Marvdasht Branch, Islamic Azad University, Marvdasht, Iran,

2 Young Researchers and Elite Club, Marvdasht Branch, Islamic Azad University, Marvdasht, Iran

Abstract

Imidazo[2,1-b]thiazoles are obtaind in excellent yields from the addition reaction between thiohydantoin and ethylbromopyruvate. These imidazo[2,1-b]thiazoles in the presence of p-TSA in boiling toluene refluxed for 2.5 hours led to imidazo[2,1-b]thiazole-3-carboxylates in elimination reactions

Keywords


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