Home Articles List Article Information
International Journal of Heterocyclic Chemistry
Journal Archive
Volume Volume 7 (2017)
Volume Volume 6 (2016)
Volume Volume 5 (2015)
Volume Volume 4 (2014)
Volume Volume 3 (2013)
Volume Volume 2 (2012)
Volume Volume 1 (2011)
Mohammadi, M. (2016). TiO2 nanoparticles/melamine Tri sulfonic acid for biginelli syntheis under solvent-free conditions. International Journal of Heterocyclic Chemistry, 6(1), 32-40.
Mohammad Kazem Mohammadi. "TiO2 nanoparticles/melamine Tri sulfonic acid for biginelli syntheis under solvent-free conditions". International Journal of Heterocyclic Chemistry, 6, 1, 2016, 32-40.
Mohammadi, M. (2016). 'TiO2 nanoparticles/melamine Tri sulfonic acid for biginelli syntheis under solvent-free conditions', International Journal of Heterocyclic Chemistry, 6(1), pp. 32-40.
Mohammadi, M. TiO2 nanoparticles/melamine Tri sulfonic acid for biginelli syntheis under solvent-free conditions. International Journal of Heterocyclic Chemistry, 2016; 6(1): 32-40.

TiO2 nanoparticles/melamine Tri sulfonic acid for biginelli syntheis under solvent-free conditions

Article 4, Volume 6, Issue 1, Spring 2016, Page 32-40  XML PDF (664 K)
Document Type: Original Paper
Author
Mohammad Kazem Mohammadi
Department of chemistry, Ahvaz Branch, Islamic Azad University, Ahvaz, Iran
Abstract
TiO2 nanoparticles/melamine Tri sulfonic acid (MTSA) supported on silica gel as an efficient catalytic system for simple, one pot, solvent-free and environmentally benign process for synthesis of dihydropyrimidines via Biginelli reaction at 110 °C is described. It was found that the catalyst is reusable and exhibited remarkable activity. The catalyst can be easily separated and reused several times without appreciable loss of activity. The availability and recoverability of the catalytic system with easy operation and work up make this catalytic system attractive for organic synthesis.
Keywords
TiO2 nano particles; Biginelli reaction; dihydropirimidinone; Solvent-free
References
  1. J.H. Clark, Green Chem,1, 1, (1999).
  2. M. Schnürch, M. Holzweber, M.D. Mihovilovic and P. Stanetty, Green Chem.,  9, 139, (2007).
  3. B.F. Mirjalili, M.A. Zolfigol, A. Bamoniri and A. Hazar, J. Braz. Chem. Soc., 16, 877 (2005).
  4. R.W. Armstrong, A.P. Combs, P.A. Tempest, S.D. Brown and T.A. Keating, Acc. Chem. Res., 29, 123 (1996).
  5. A.R. Kiasat and M. Fallah-Mehrjardi, J. Braz. Chem. Soc., 19, 1595. (2008).
  6. M.A. Bigdeli, S. Jafari, G.H. Mahdavinia and H. Hazarkhani, Catal. Commun., 8, 1641 (2007).
  7. P. Biginelli, Gazz. Chim. Ital., 23, 360. (1893).
  8. C.O. Kappe, TetrahedronLett., 49, 6937 (1993).
  9. C.O. Kappe, Acc. Chem. Res., 33, 879 (2000).
  10. J.P. Wan and Y. Liu, Synthesis, 23, 3943 (2010).
  11. A. Karamat, M.A. Khan and A. Sharif, J. Chin. Chem. Soc., 57, 1099 (2010).
  12. A.D. Patil, N.V. Kumar, W.C. Kokke, M.F. Bean, A.J. Freyer, C. DeBrosse, S. Mai, A. Truneh and B. Carte, J. Org. Chem., , 60, 118 (1995).
  13. K. Folkers, H.J. Harwood, T.B. Johnson, J. Am. Chem. Soc., 54, 3751 (1932).
  14. K. Folkers and T.B. Johnson, J. Am. Chem. Soc., ,55, 3784 (1933).
  15. S.K.Kundu,A. Majee and A.Hajra, Ind. J. chem., ,48B,408 (2009).
  16. T. Jin, S. Zhang and T. Li, Synth. Commun., , 32, 1847 (2002).
  17. P. Salehi, M. Dabiri, M.A. Zolfigol and M.A. BodTiO2hiFard, Tetrahedron Lett., 44, 2889 (2003).
  18. S. Tu, F. Fang, S. Zhu, T. Li, X. Zhang and Q. Zhuang, Synlett.,  3, 537 (2004).
  19. H. Adibi, H.A. Samimi and M. Beygzadeh, Catal. Commun., 8, 2119 (2007).
  20. Y. Yu, D. Liu, C. Liu and G. Luo, Bioorg. Med. Chem. Lett., 17, 3508 (2007).
  21. E.H. Hu, D.R. Sidler and U.H. Dolling, J. Org. Chem.,  63, 3454 (1998).
  22. Y. Ma, C. Qian, L. Wang and M. Yang, J. Org. Chem.,  65, 3864 (2000).
  23. K.A. Kumar, M. Kasthuraiah, C.S. Reddy andC.D. Reddy, Tetrahedron Lett., 42,7873 (2001).
  24. V. Mirkhani, M. Moghadam and S. Tangestaninejad, J. Iran. Chem. Soc., 8, 611 (2011).
  25.  G. Maiti, P. Kundu and C. Guin, Tetrahedron Lett, 44, 2757 (2003).
  26. M. Tajbakhsh, B. Mohajerani, M.M. Heravi and A.N. Ahmadi, J. Mol. Catal. A. Chem., 236,216 (2005).
  27. S.K. De and R.A. Gibbs, Synthesis,11, 1748 (2005).
  28. A.K. Mitra and K. Banerjee, Synlett., 10, 1509-1511. (2003).
  29. T. Jin, S. Zhang and T. Li, Synth. Commun., 32, 1847-1851. (2002).
  30. G.L. Zhang and X.H. Cai, Synth. Commun., 2005, 35, 829 (1993).
  31. G. Aridoss and Y.T. Jeong, Bull. Korean Chem. Soc.,31, 863 (2010).
Statistics
Article View: 395
PDF Download: 709