Hashema, H., Hemdanb, M., Youssef, A., El-Mariaha, F. (2017). Synthesis of Some Quinazoline Derivatives Functionalized with3-Heterocycles Side Chain. International Journal of Heterocyclic Chemistry, 7(2), 36-52.
Heba E. Hashema; Magdy M. Hemdanb; Ahmed S.A. Youssef; Fatma A. El-Mariaha. "Synthesis of Some Quinazoline Derivatives Functionalized with3-Heterocycles Side Chain". International Journal of Heterocyclic Chemistry, 7, 2, 2017, 36-52.
Hashema, H., Hemdanb, M., Youssef, A., El-Mariaha, F. (2017). 'Synthesis of Some Quinazoline Derivatives Functionalized with3-Heterocycles Side Chain', International Journal of Heterocyclic Chemistry, 7(2), pp. 36-52.
Hashema, H., Hemdanb, M., Youssef, A., El-Mariaha, F. Synthesis of Some Quinazoline Derivatives Functionalized with3-Heterocycles Side Chain. International Journal of Heterocyclic Chemistry, 2017; 7(2): 36-52.
Synthesis of Some Quinazoline Derivatives Functionalized with3-Heterocycles Side Chain
1Department of Chemistry, College for Girls, Ain Shams University, Helioplis, Cairo 11457, Egypt
2Department of Chemistry, Faculty of Science, Ain Shams University, Abbassia, Cairo 11566, Egypt
Abstract
Utilization of benzoxazinone for synthesis quinazolinone derivatives with 3-heterocycle side chain. treatment of benzoxazinon 1 with cyano acetohydrazide or thionocarbohydrazide gave the quinazolinone derivatives 2 or 12. quinazolinone 2 has been utilized as synthon for new pyridinone, oxazet, thiazole, thiazolidinone and quinazolinone derivatives. Thiosemicarbazide and thiosemicarbazone derivatives are synthesized from quinazolinone 12 by different route. The structures of the new compounds were established on the basis of IR, 1HNMR, mass spectral data, and elemental analysis.
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