Catalytic effect of green zinc oxide nanoparticles on multi –component reactions

Document Type: Original Paper


1 Department of Chemistry, College of Science,Khouzestan Science and Research Branch, Islamic Azad University,Ahvaz,Iran

2 Department of Chemistry, Khoramshahr University of Marine Science and Technology


In this study, multi component Hantzsch reaction was carried out between various  Aromatic Aldehyde with Dimedone,Ethyl acetateand ammonium acetate to produce polyhydroquinolinederivatives under solvent-free conditions at 110oC by a (Zinc oxide  nanocatalyst) as effective Lewis acid. The remarkable advantages offered by this method compared with other methods are a green catalyst, simple work-up procedures, fast reactions, a long high yields.