Department of Chemistry, Faculty of Sciences, Islamic Azad University, Central Tehran Branch, Iran
Abstract
An efficient and expeditious catalyst-free procedure was developed for the one- pot synthesis of 1, 4-dihydropyridine derivatives via the three-component reaction of various aldehydes, ethyl acetoacetate, and ammonium acetate in PEG-400. The reaction was carried out at 110°С and the products were obtained in good to high yields.
Ezabadi, A., Tosan, F. (2018). A Novel protocol for synthesis of Hantzsch 1, 4- dihydropyridines using PEG-400 as a reaction medium and under catalyst-free condition. International Journal of Heterocyclic Chemistry, 8(3), 5-11.
MLA
Ali Ezabadi; Fatemeh Tosan. "A Novel protocol for synthesis of Hantzsch 1, 4- dihydropyridines using PEG-400 as a reaction medium and under catalyst-free condition". International Journal of Heterocyclic Chemistry, 8, 3, 2018, 5-11.
HARVARD
Ezabadi, A., Tosan, F. (2018). 'A Novel protocol for synthesis of Hantzsch 1, 4- dihydropyridines using PEG-400 as a reaction medium and under catalyst-free condition', International Journal of Heterocyclic Chemistry, 8(3), pp. 5-11.
VANCOUVER
Ezabadi, A., Tosan, F. A Novel protocol for synthesis of Hantzsch 1, 4- dihydropyridines using PEG-400 as a reaction medium and under catalyst-free condition. International Journal of Heterocyclic Chemistry, 2018; 8(3): 5-11.
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