Kiasat, A. (2018). One-Pot Synthesis of Phenytoin Analogs in Solvent free Conditions Via the Use of Pestle/ Mortar. International Journal of Heterocyclic Chemistry, 8(4), 33-37.
Alireza Kiasat. "One-Pot Synthesis of Phenytoin Analogs in Solvent free Conditions Via the Use of Pestle/ Mortar". International Journal of Heterocyclic Chemistry, 8, 4, 2018, 33-37.
Kiasat, A. (2018). 'One-Pot Synthesis of Phenytoin Analogs in Solvent free Conditions Via the Use of Pestle/ Mortar', International Journal of Heterocyclic Chemistry, 8(4), pp. 33-37.
Kiasat, A. One-Pot Synthesis of Phenytoin Analogs in Solvent free Conditions Via the Use of Pestle/ Mortar. International Journal of Heterocyclic Chemistry, 2018; 8(4): 33-37.
One-Pot Synthesis of Phenytoin Analogs in Solvent free Conditions Via the Use of Pestle/ Mortar
Department of Chemistry , Shahid Chamran University , Ahwaz , Iran
Abstract
phenytoine derivatives were synthesized , via the pinacol condensation with the reaction of 1,3- diphenyl- propane- 1,3- dione (benzyl) analogs with urea or thiourea in presence of slica gel and solid KOH as Solid phase catalyst in the mortar / pestle at room temperatures. The reaction was completed at short reaction times (approximately 15min) and pure products were obtained with high yields (81-94%).
Top