Golkari, M. (2019). Solvent-free One Pot Biginelli Method for Synthesis of new Dihydropyrimidinone compounds. International Journal of Heterocyclic Chemistry, 9(1), 60-66.
Masih Golkari. "Solvent-free One Pot Biginelli Method for Synthesis of new Dihydropyrimidinone compounds". International Journal of Heterocyclic Chemistry, 9, 1, 2019, 60-66.
Golkari, M. (2019). 'Solvent-free One Pot Biginelli Method for Synthesis of new Dihydropyrimidinone compounds', International Journal of Heterocyclic Chemistry, 9(1), pp. 60-66.
Golkari, M. Solvent-free One Pot Biginelli Method for Synthesis of new Dihydropyrimidinone compounds. International Journal of Heterocyclic Chemistry, 2019; 9(1): 60-66.
Solvent-free One Pot Biginelli Method for Synthesis of new Dihydropyrimidinone compounds
Department of polymer engeeniering, Tehra Science and Reaserch Branch, Islamic Azad University,Tehran, Iran
Abstract
An effective one-pot synthesis of dihydropyrimidinonoes in solvent free conditions using CuCl2 as an inexpensive and readily available reagent through Biginelli condensation reaction of aldehyde derivatives, 1,3-dicarbonyl compounds and urea is described. Excellent yields, short reaction times for formation of the products and simple work-up are attractive features of this green protocol.
Top